Wait—Blood Sugar Affects Your Heart? Here’s What To Know

Plus, 5 ways to promote better blood sugar & heart health

FrankLin

Feb 21, 2025 - 21:02

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Wait—Blood Sugar Affects Your Heart? Here’s What To Know

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Author:

February 21, 2025

Assistant Health Editor

By Ava Durgin

Assistant Health Editor

Ava Durgin is the Assistant Health Editor at mindbodygreen. She is a recent graduate from Duke University where she received a B.A. in Global Health and Psychology. In her previous work, Ava served as the Patient Education Lead for Duke Hospital affiliated programs, focusing on combating food insecurity and childhood obesity.

Image by iStock - miodrag ignjatovic

February 21, 2025

When you think of heart health, your mind probably jumps to cholesterol or blood pressure. But there’s another factor that deserves attention: your blood sugar. It turns out that blood sugar fluctuations can influence heart rate in both the short and long term, potentially contributing to conditions like atrial fibrillation (AFib) and other cardiovascular issues.

How blood sugar affects your heart

Short-term effects: Heart rate spikes

Both low blood sugar (hypoglycemia) and high blood sugar (hyperglycemia) can trigger a temporary increase in heart rate or cause palpitations—those unsettling sensations when your heart races or skips beats.

Low blood sugar: When glucose levels dip, the brain senses an “energy emergency” and triggers the release of fight-or-flight hormones like adrenaline and cortisol. These hormones increase your heart rate to help mobilize glucose reserves.High blood sugar: A spike after eating a high-carb meal may activate the sympathetic nervous system (your body’s stress response) while suppressing the parasympathetic system (your relaxation response). This combination elevates heart rate.

Research backs up these physiological responses. A 2022 study found that individuals with higher fasting glucose levels often had higher resting heart rates—likely due to increased sympathetic activity and insulin resistance.

The long-term connection: Blood sugar & cardiac arrhythmias

Repeated blood sugar spikes aren’t just a temporary nuisance. Over time, they can damage your cardiovascular system, increasing the risk of serious conditions like atrial fibrillation (AFib).

AFib is a common heart arrhythmia where the heart’s upper chambers beat irregularly, impairing blood flow. This condition is linked to higher risks of stroke and heart failure.

A study published in 2020 found that individuals with type 2 diabetes had a 35% higher risk of developing AFib compared to the general population. The risk was even higher for women under 55, who faced a 136% increased likelihood of AFib compared to non-diabetic controls.

The study also showed a clear relationship between blood sugar control and AFib risk:

For every 20 mg/dL increase in blood sugar, the risk of AFib increased by 11%.Even people with well-controlled blood sugar faced a 16% increased risk of AFib compared to controls.

Prediabetes & major adverse cardiac events

Prediabetes is a condition where blood sugar levels are elevated but not high enough to meet the criteria for type 2 diabetes. While often overlooked, it has now been recognized as a significant risk factor for major adverse cardiac and cerebrovascular events (MACCE)—particularly in individuals with atrial fibrillation (AF).

A recent population-based study analyzed over 2.9 million AF-related hospitalizations, identifying 47,505 cases involving prediabetic patients. The research aimed to explore the relationship between prediabetes and MACCE, which includes cardiac arrest, stroke, and all-cause inpatient mortality.

The study found that prediabetic AF patients demonstrated a 34% higher likelihood of experiencing MACCE compared to non-prediabetics.

These findings highlight the crucial importance of managing blood sugar levels, as prediabetes significantly increases the risk of severe cardiac events in individuals with atrial fibrillation, reinforcing the vital connection between heart health and blood sugar control.

Why does this happen?

Researchers believe several mechanisms are at play:

Inflammation and oxidative stress: Consistently high blood sugar leads to the formation of advanced glycation end products, harmful compounds that trigger inflammation and damage tissues, including heart cells.Nervous system dysfunction: Chronic high glucose levels can impair the autonomic nervous system, which regulates heart rate.Vascular damage: Elevated blood sugar promotes the buildup of arterial plaque, raising the risk of heart attack and stroke.

What you can do for better blood sugar & heart health

The good news? Small, consistent lifestyle changes can make a big difference.

Craft balanced meals: Always pair carbs with protein, fiber, and healthy fats to prevent sharp blood sugar spikes.Get moving after meals: Using your muscles after eating can help stabilize blood sugar levels and support heart health. This could be a quick walk, a couple squats, or a little dance party. Monitor your glucose: Using a continuous glucose monitor can help you understand how your body responds to different foods and activities.Watch your resting heart rate: While minor increases after meals are normal, significant or persistent spikes might warrant a conversation with your doctor.Stay mindful of stress: Stress can affect both blood sugar and heart rate, so techniques like meditation or breathwork may be beneficial.

The takeaway

The connection between blood sugar and heart health is an evolving area of research. But one thing is clear: keeping your glucose levels stable isn’t just about preventing diabetes—it’s essential for protecting your heart. By adopting simple lifestyle strategies, you can take proactive steps to support both metabolic and cardiovascular well-being.